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Here we demonstrate that DNL343 reduces ISR activation and neurodegeneration brought on acutely by an optic nerve crush (ONC) injury or chronically by a germline eIF2B LOF mutation in mice. We also present that DNL343 therapy, initiated in a late phase of ailment which additional accurately replicates a scientific dosing https://ginsenoside-ra114889.blogunok.com/28488497/top-t16ainh-a01-secrets

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