Substitution at R3 that has a halogen or alkoxy group (74f–74i) brought about a slight increase in mobile potency Along with the halide analogs (74g–h) exhibiting maximum the potency inside the group. Additional optimization triggered the discovery of 74i–j, with 74k as essentially the most Lively compound inside the collection https://indazoleproducts42086.blogofoto.com/62688586/about-indazole-synthesis-review