See the Interactions area For additional details. Also convey to your Health care company if you have applied clonidine transdermal patches (Catapres-TTS) and have experienced an allergic response. Clonidine treats higher blood pressure by stimulating αtwo receptors during the brainstem, which decreases peripheral vascular resistance, lowering blood pressure level. https://www.proleviate.com/post/the-new-pain-killer-conolidine