Pentobarbital will decrease the level or effect of ketoconazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of amiodarone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Acting as both a sedative and a hypnotic, pentobarbital can be prescribed for the short-term tre... https://yoursocialpeople.com/story5725646/tutto-ci%C3%B2-che-riguarda-what-is-nembutal-pentobarbital